Automated sample preparation, extraction and concentration for GC–MS

Automated sample preparation, extraction and concentration for GC–MS
Centri 360: The ultimate automated multi-mode extraction and enrichment platform
Centri 360: The ultimate automated multi-mode extraction and enrichment platform
Centri 90: Dedicated to high sensitivity, high throughput routine analysis
Centri 90: Dedicated to high sensitivity, high throughput routine analysis
Centri 180: All the functionality of Centri 90, plus automated TD and HiSorb functionality
Centri 180: All the functionality of Centri 90, plus automated TD and HiSorb functionality

Each Centri® platform from Markes International offers high-sensitivity unattended sampling and pre-concentration of VOCs and SVOCs in liquid, solid and gaseous samples. Using Markes’ advanced trapping technology, Centri enhances the sensitivity and extends performance of several popular sample introduction techniques for GC–MS:

  • HiSorb™ high-capacity sorptive extraction.
     
  • Headspace and headspace–trap.
     
  • Method-compliant thermal desorption.
     
  • SPME and SPME–trap.

Compatible with all major brands of GC/GC–MS, the Centri product range allows you to address challenging applications, delivering exceptional performance from research and routine analysis.

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The Centri range of products

Centri 90

A platform for high-throughput, routine, high-sensitivity automated analysis using headspace- and SPME- and SPME Arrow-based workflows, with additional chromatographic performance provided by trap-based preconcentration.

Along with advanced options for water management, Centri 90 provides excellent analytical performance across a wide analyte range, and especially for early-eluting VVOCs. Conventional GC injection modes remain available, allowing you to maintain existing workflows while also evaluating the benefits of preconcentration using the focusing trap.

The platform is Multi-Gas engable, meaning that you can work with your choice of helium, nitrogen or hydrogen carrier gasses to future-proof your laboratory, cost-saving and further productivity enhancements.

Centri 90 has a modular design and is upgradable for thermal desorption and HiSorb, high-capacity sorptive extraction (Centri 180 configuration).

 

Centri 180

Featuring all that Centri 90 offers but with extended capability for thermal desorption (from sorbent tubes) and HiSorb™ high-capacity sorptive extraction, which is provided by a multi-tube autosampler.

 

Centri 360

Markes’ award-winning Centri 360 is the ultimate automated multi-mode extraction and enrichment platform for GC–MS.

Centri 360 is designed for researchers needing comprehensive sample profiling, and who use multiple sample preparation techniques. Powered by best-in-class robotic automation, Centri 360 gives unrivalled flexibility for unattended, rapid and efficient extraction and enrichment of VOCs and SVOCs. With its multiple sampling modes and modular design, Centri offers maximum versatility for liquid, solid and gaseous samples.

Centri 360 offers the full range of fully-automated sample preparation techniques (headspace, solid-phase microextraction (SPME), HiSorb™ high-capacity sorptive extraction, and thermal desorption), each with analyte trapping for sensitivity enhancement. The Centri 360 also offers direct liquid injection to the GC.

 

WHY USE CENTRI?

  • Cryogen-free analyte trapping provides high sensitivity by delivering a sharp, concentrated band of vapour to the GC.

  • The only systems that offer full automation of sorptive extraction, using inert HiSorb probes.

  • Sample splitting and re-collection allows repeat analysis without the need to repeat extraction steps.

  • Multi-step enrichment improves detection limits and allows:

    • Samples resulting from different matrix modifications to be combined

    • Matrix levels to be reduced by performing several sequential short extractions, rather than a single long extraction.

  • Prep-ahead mode and automatic tool change result in increased productivity.

  • The modular nature of Centri makes it a futureproof system, enabling analytical capabilities to be easily extended for greater versatility.

 

 


Applications

Uncovering hidden compositional changes in breath profiles using untargeted chemometric workflows
This study describes the use of thermal desorption (TD) and GC×GC–TOF MS for exploratory profiling of biomarkers in breath, coupled with innovative data mining tools to uncover hidden compositional changes using automated untargeted workflows.
Details
Reverse-engineering the aroma of plant-based meat substitutes
This study describes the use of headspace sorptive extraction with GC×GC–TOF MS to compare the volatile profiles of ground meat and plant-based substitutes.
Details
Investigating the quality of Darjeeling teas using comprehensive VOC fingerprints
This study demonstrates the use of immersive sorptive extraction and GC×GC–TOF MS to determine the characteristic flavour compounds in Darjeeling teas. Comparative analysis of different tea types and grades will be shown using streamlined workflows to improve quality assessment.
Details

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